The goal of this project is to detect Alzheimer’s disease (AD) at a very early stage, even before symptoms occur. The idea is to combine two spectroscopy methods, Raman spectroscopy and Fourier transform infrared spectroscopy (FTIR), that deliver complementary information. In collaboration with a biomedical research institute and the University of the Basque Country, we investigate human samples of cerebrospinal fluid (CSF) from Alzheimer’s patients as well as volunteering persons.

Job description

• Measurement of Raman spectra of human CSF samples

• Measurement of FTIR spectra of human CFS samples

• Increase of concentration of biomarkers by ultracentrifugation

• Data analysis by multivariate analysis methods

• Correlation of data with medical status in collaboration with external partner

Main outcome of the project

• Detection of amyloid beta peptides at low concentrations in CSF

• Multivariate analysis methods combining two spectroscopy methods

• Correlation of AD status with spectroscopic measurements

We encourage highly motivated candidates to carry out their final Master’s thesis in an international multidisciplinary research environment. For more information about our group http://www.nanogune.eu/nanoengineering.

Application:

If you are a master student and you are interested in this project, please get in touch with the scientist in charge: Andreas Seifert (a.seifert@nanogune.eu)

To apply for a master scholarship fill in the form below and follow the instructions and recomendations of the general call open until 20 September 2019.